This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. Here are answers to some frequently asked questions about Zetia. You can also ask your pharmacist for information on how to dispose of your medication. Memory loss isnt a side effect of Zetia. upper respiratory tract infection, including the common cold. A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Learn about side effects, dosage, and more. However, animal studies dont always predict what will happen in humans. Many rare diseases have limited information. A medication timer may be useful, too. The autonomic nervous system is in charge of all bodily functions that we don't have to think about, such as: The sympathetic nervous system is part of the autonomic nervous system. (For information on side effects, see the Zetia side effects section above.). Both drugs are typically taken once each day. Would a lower dose of Zetia help to reduce my risk of side effects? For more information on these side effects, see Side effect details below. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. However, it isnt known how Zetia may affect these risks. The heart beats faster to pump it up to the brain, but with little success. Zetia has been found in breast milk during animal studies. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. Bock's fainting spells are one of the hallmarks of POTS. In clinical studies of Zetia used with statin drugs to treat primary hyperlipidemia in adults and in children ages 10 years and older: It isnt known how long adults and children experienced muscle pain while taking Zetia with statin drugs in these clinical studies. Zetia is approvedto treat certain forms of high cholesterol in children ages 10 years and older. However, 0.5% of adults and children who took Zetia with a statin drug experienced muscle pain so bothersome that they had to stop treatment. Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. Zetia is a brand-name prescription drug. Note: Zetia isnt approved to lower these types of cholesterol: Cholesterol is measured in several ways. The generic form of Zetia costs about the same as the generic form of Lipitor. Also tell them about any vitamins, herbs, and supplements you use. Also, tell your doctor right away if you become pregnant while taking this drug. Nausea/Vomiting. If you would like to report to the FDA a side effect youve had with Zetia, you can do so through MedWatch. And generics tend to cost less than brand-name drugs. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. However, if the side effects last longer than . Examples of statin drugs include: Learn more about how grapefruit may interact with medications. Before approving coverage for Zetia, your insurance company may require you to get prior authorization. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Physicians who treat dysautonomia can be located on our Physician List. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. The following lists contain some of the key side effects that may occur while taking Zetia. It's Aimee Esther here! In addition to Goff's specific symptoms, POTS can be associated with neurocognitive impairments or "brain fog"; problems with body temperature regulation; gastroenterological symptoms like nausea, abdominal pain, diarrhea, or constipation; and dark red-blue discoloration of the legs. Less cholesterol entering your liver allows your liver to break down the cholesterol it already has stored. What are the serious side effects of Zetia? Zetia can cause certain side effects, some of which are more common than others. Zetia and Crestor are both brand-name drugs. If you have questions about using Zetia and cholestyramine together, talk with your doctor. The most common side effects of Zetia include: muscle or joint pain, In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). They may have a preference for one version or the other. Zetia can interact with several other medications. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. Recently, POTS has been diagnosed in some people who have had COVID-19. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. It wasnt reported during studies of the drug. * Zetia is also approved to treat these conditions in children ages 10 years and older. Statins lower cholesterol by preventing your liver from making new cholesterol. This is not a complete list of side effects and others may occur. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. This section doesnt contain all drugs that may interact with Zetia. For more information about Zetia, including details about its uses, see this in-depth article on the drug. Zetia contains the active drug ezetimibe. * To learn more about this side effect, see the Side effects explained section below. If you develop serious side effects while taking Zetia, call your doctor right away. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. And your doctor can use this information to adjust your treatment plan if needed. You can take Zetia with or without food. Call your doctor right away if you have serious side effects. As with all medications, the cost of Zetia can vary. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. (A class of drugs is a group of medications that work in a similar way.) Statins are cholesterol drugs that may be taken with Zetia. Cardiology 33 years experience. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. What is considered high cholesterol? Symptoms: This section is currently in development. They may want to select a different treatment option for you. But its not clear whether this side effect occurred in studies of the drug. Zetia generally costs more than Crestor. POTS is commonly associated with low levels of fluid. For more information, see the prescribing information for Zetia and Crestor. Some people witness mild symptoms, some have a big impact on their lives due . The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . These lists contain examples of serious side effects that can occur with Lipitor or with both drugs (when taken individually). Lipitor is also FDA-approved for the following conditions when used with a low-cholesterol diet: primary dysbetalipoproteinemia in adults (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), liver complications, such as high levels of, Both Zetia and Crestor are FDA-approved to treat the following conditions* when used with a. Crestor is also FDA-approved for the following conditions in adults when used with a low-cholesterol diet: primary dysbetalipoproteinemia (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), pain on the right side of your body, below your ribs, in adults as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin drug), in adults in combination with a fenofibrate, in combination with statins, in people with hepatic disease, in combination with statins, in people with elevated hepatic transaminases, in combination with statins, during pregnancy or in someone planning to become pregnant, in combination with statins, while breastfeeding, in people who have a known allergy to Zetia. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. Increased liver enzymes can be a sign of liver damage. There arent any herbs or supplements that have been specifically reported to interact with Zetia. Zetia is also available in a generic form called ezetimibe. (Primary hyperlipidemia is also called primary high cholesterol.) But if they become more severe or dont go away, talk with your doctor or pharmacist. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. Symptoms of a swollen gallbladder may include: Tell your doctor if you experience gallstones while using Zetia with fenofibrate. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). Zetia, Baclofen, and Xanax are not known to cause itching at all, but the Xanax can cause problems with memory which you do describe. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. However, studies have found both Zetia and Crestor to be effective for lowering cholesterol. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. Dont take an extra dose to make up for your missed dose. However, some people have reported experiencing memory loss when taking statin drugs. Serious side effects and their symptoms can include: * You may be more likely to experience this side effect if you take Zetia with a statin drug than if you take Zetia alone. Currently GARD aims to provide the following information for this disease: Population Estimate: This section is currently in development. Postural orthostatic tachycardia syndrome (POTS) is a condition that causes a number of symptoms when you transition from lying down to standing up, such as a fast heart rate, dizziness and fatigue. tender, swollen glands in neck. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. If you already have liver problems, taking Zetia may worsen your condition. Crestor is part of the statin drug class. Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . What Are the Injectable Alternatives to Statins? Zetia may not be right for you if you have certain medical conditions or other factors affecting your health. Other interactions can increase side effects or make them more severe. Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. Allergic reaction. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. But its not clear whether this side effect occurred in studies. If your muscle-related side effects dont go away or become severe, tell your doctor right away. The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. There arent any foods that have been specifically reported to interact with Zetia. Or they may recommend that you stop taking the medication. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. They can both be taken with or without food. Learn about the common, mild, and serious side effects it can cause and how to manage them. For instance, some interactions can interfere with how well a drug works. Grapefruit can prevent the breakdown of these drugs in your body. Both Zetia and Crestor come as tablets that are swallowed. This is because fenofibrate is the only fibrate Zetia was studied with, so it isnt known whether Zetia and other fibrate drugs are safe to use together. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Phase IV trials are used to detect adverse drug . Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. They didnt take Zetia with other drugs that also treat high cholesterol. If you have questions about weight changes while using Zetia, talk with your doctor. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. muscle pain while taking ezetimibe with a statin. An allergic reaction is possible after using Zetia. After stopping Zetia treatment, their liver enzymes levels went back down. Taking Zetia with a statin may cause this side effect. Weight gain isnt a side effect reported in clinical studies of Zetia. The bottom line: Zetia may cause fewer side effects than statins (though some clinicians might dispute that) but Zetia may cause muscle problems and other adverse reactions. Merck, the manufacturer of Zetia, offers a Patient Assistance Program. To help you decide whether Zetia is a good treatment choice for you, talk with your doctor. The results showed that people taking statins reported decreased muscle-related symptoms after adding a CoQ10 supplement to their regimen. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. In studies, some people had to stop taking Zetia because of this side effect. Cholesterol can also be found in foods such as eggs, cheese, and meat. Also, if you have a history of heavy drinking or liver damage, be sure to tell your doctor before you begin taking Zetia. The generic is considered to be as safe and effective as the original drug. Learn more about the link. Depending on your age or other medical conditions you may have, you may be at higher risk of developing rhabdomyolysis while taking Zetia. Do not use more Zetia than your doctor recommends. The children took Zetia and simvastatin or simvastatin alone. Based on animal studies, Zetia may cause harm to the fetus when taken by a pregnant woman. (Mixed hyperlipidemia is also known as mixed high cholesterol.). More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. This is because large meals can cause blood to pool excessively in the abdomen. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. These symptoms could be life threatening and require immediate medical care. People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. Examples of other drugs that may be used to treat primary high cholesterol include: Examples of other drugs that may be used to treat mixed high cholesterol include: Examples of other drugs that may be used to treat homozygous familial hypercholesterolemia include: Examples of other drugs that may be used to treat homozygous sitosterolemia include: You may wonder how Zetia compares with other medications that are prescribed for similar uses. These conditions can raise your risk of muscle problems while taking Zetia. Zetia and Lipitor have some similar side effects and others that vary. Crestor is available in a generic form called rosuvastatin. It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. Energy Drinks, such as Red Bull, should be avoided in those with POTS. stuffy nose. Risk factors for muscle-related problems. For more information, see the How Zetia works section below. Avoid eating foods high in fat or cholesterol, or Zetia will not be as effective. You likely wont notice Zetia working in your body. You should always consult your doctor or another healthcare professional before taking any medication. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. Therefore, you shouldnt breastfeed if youre taking Zetia with a statin drug. Leqvio is a prescription drug used to lower cholesterol. Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. This active drug is also available as a generic medication. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. You may find your symptoms are worse in the morning, and they may change from day to day. People with this condition have high levels of plant sterols. If youre taking Zetia, talk with your doctor or pharmacist to see whether CoQ10 could be a good supplement for you. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. You may be able to find testimonials online from people who take Zetia. Zetia isnt a statin drug. Specifically, Zetia is used along with a low-cholesterol diet to treat: Zetia is approved to treat these conditions in certain situations. Talk with your doctor to learn more about which medications are right for you. We've provided a list of the best at-home tests for. However, you shouldnt stop taking Zetia without first talking with your doctor. Talk with your doctor right away if you have fever or chills with your joint pain. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. It isnt known how often this side effect occurred with Zetia in clinical studies. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. You cannot reliably predict how your body will react to a treatment based on someone elses experience. High cholesterol can raise your risk of heart disease. What foods should I avoid while taking Zetia. Youll likely take Zetia once a day. Its called homozygous because the genes that cause this condition are inherited from both parents. Taking Zetia with cyclosporine (a drug that suppresses your immune system) can raise the levels of both medications in your body. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. That of statins include Lipitor ( atorvastatin ), Crestor ( rosuvastatin ), Crestor rosuvastatin! 10 years and older studies have found both Zetia and Crestor to be effective lowering. Low-Cholesterol diet to treat hair loss due to a treatment based on animal studies always! Time youre considering taking a supplement, its important to discuss this with your doctor if they become severe... Foods such as eggs, cheese, and triglycerides are one Part of your total cholesterol level than! Pots has been found in foods such as eggs, cheese, and meat both drugs ( when taken a... 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